Inhibition of the mTOR Pathway Exerts Cardioprotective Effects Partly through Autophagy in CLP Rats

BACKGROUND: Sepsis-induced myocardial dysfunction is a severe clinical problem. Recent studies have indicated that autophagy and myocardial energy depletion play a major role in myocardial dysfunction during sepsis, a mechanistic target of rapamycin (mTOR) as a master sensor of energy status and aut...

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Detalles Bibliográficos
Autores principales: Han, Wen, Wang, Hao, Su, Longxiang, Long, Yun, Cui, Na, Liu, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046132/
https://www.ncbi.nlm.nih.gov/pubmed/30050390
http://dx.doi.org/10.1155/2018/4798209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046132/
https://www.ncbi.nlm.nih.gov/pubmed/30050390
http://dx.doi.org/10.1155/2018/4798209

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