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A Validated LC-MS/MS Method for Simultaneous Determination of Six Aconitum Alkaloids and Seven Ginsenosides in Rat Plasma and Application to Pharmacokinetics of Shen-Fu Prescription

A sensitive and reliable LC-MS/MS method has been developed and validated for simultaneous determination of six Aconitum alkaloids (aconitine, hypaconitine, mesaconitine, benzoylaconitine, benzoylhypacoitine, and benzoylmesaconine) and seven ginsenosides (Rb(1), Rb(2), Rc, Rd, Re, Rf, and Rg(1)) in...

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Detalles Bibliográficos
Autores principales: Ouyang, Huizi, Liu, Fang, Tang, Zhidan, Chen, Xiaopeng, Bo, Fang, Liu, Huaming, Chang, Yanxu, He, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046171/
https://www.ncbi.nlm.nih.gov/pubmed/30050589
http://dx.doi.org/10.1155/2018/5107083