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Regulatory RNA binding proteins contribute to the transcriptome-wide splicing alterations in human cellular senescence

Dysregulation of mRNA splicing has been observed in certain cellular senescence process. However, the common splicing alterations on the whole transcriptome shared by various types of senescence are poorly understood. In order to systematically identify senescence-associated transcriptomic changes i...

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Detalles Bibliográficos
Autores principales: Dong, Qiongye, Wei, Lei, Zhang, Michael Q., Wang, Xiaowo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046225/
https://www.ncbi.nlm.nih.gov/pubmed/29936497
http://dx.doi.org/10.18632/aging.101485