Inactivation of hepatic ATRX in Atrx Foxg1cre mice prevents reversal of aging-like phenotypes by thyroxine

ATRX is an ATP-dependent chromatin remodeler required for the maintenance of genomic integrity. We previously reported that conditional Atrx ablation in the mouse embryonic forebrain and anterior pituitary using the Foxg1cre driver causes reduced health and lifespan. In these mice, premature aging-l...

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Detalles Bibliográficos
Autores principales: Rowland, Megan E., Jiang, Yan, Beier, Frank, Bérubé, Nathalie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046231/
https://www.ncbi.nlm.nih.gov/pubmed/29883366
http://dx.doi.org/10.18632/aging.101462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046231/
https://www.ncbi.nlm.nih.gov/pubmed/29883366
http://dx.doi.org/10.18632/aging.101462

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