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No Significant Role for Smooth Muscle Cell Mineralocorticoid Receptors in Atherosclerosis in the Apolipoprotein-E Knockout Mouse Model

Objective: Elevated levels of the hormone aldosterone are associated with increased risk of myocardial infarction and stroke in humans and increased progression and inflammation of atherosclerotic plaques in animal models. Aldosterone acts through the mineralocorticoid receptor (MR) which is express...

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Detalles Bibliográficos
Autores principales: Moss, M. Elizabeth, DuPont, Jennifer J., Iyer, Surabhi L., McGraw, Adam P., Jaffe, Iris Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046374/
https://www.ncbi.nlm.nih.gov/pubmed/30038907
http://dx.doi.org/10.3389/fcvm.2018.00081