Cargando…

No Significant Role for Smooth Muscle Cell Mineralocorticoid Receptors in Atherosclerosis in the Apolipoprotein-E Knockout Mouse Model

Objective: Elevated levels of the hormone aldosterone are associated with increased risk of myocardial infarction and stroke in humans and increased progression and inflammation of atherosclerotic plaques in animal models. Aldosterone acts through the mineralocorticoid receptor (MR) which is express...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moss, M. Elizabeth, DuPont, Jennifer J., Iyer, Surabhi L., McGraw, Adam P., Jaffe, Iris Z.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046374/ https://www.ncbi.nlm.nih.gov/pubmed/30038907 http://dx.doi.org/10.3389/fcvm.2018.00081

Ejemplares similares

Mineralocorticoid Receptors in the Pathophysiology of Vascular Inflammation and Atherosclerosis
por: Moss, Mary E., et al.
Publicado: (2015)

Mineralocorticoid Receptor–Mediated Vascular Insulin Resistance: An Early Contributor to Diabetes-Related Vascular Disease?
por: Bender, Shawn B., et al.
Publicado: (2013)

Direct Regulation of Blood Pressure by Smooth Muscle Cell Mineralocorticoid Receptors
por: McCurley, Amy, et al.
Publicado: (2012)

Senescence in Vascular Smooth Muscle Cells and Atherosclerosis
por: Zha, Yiwen, et al.
Publicado: (2022)

Increased mTORC1 activity contributes to atherosclerosis in apolipoprotein E knockout mice and in vascular smooth muscle cells()
por: Ma, Kun Ling, et al.
Publicado: (2013)

Endothelial–Vascular Smooth Muscle Cells Interactions in Atherosclerosis
por: Li, Manna, et al.
Publicado: (2018)

Molecular Interactions Between Vascular Smooth Muscle Cells and Macrophages in Atherosclerosis
por: Beck-Joseph, Jahnic, et al.
Publicado: (2021)

The Role of Iron in Atherosclerosis in Apolipoprotein E Deficient Mice
por: Ma, Juan, et al.
Publicado: (2022)

Effects of p53-knockout in vascular smooth muscle cells on atherosclerosis in mice
por: Cao, Richard Yang, et al.
Publicado: (2017)

Smooth muscle-specific HuR knockout induces defective autophagy and atherosclerosis
por: Liu, Shanshan, et al.
Publicado: (2021)

PRDX2 Protects Against Atherosclerosis by Regulating the Phenotype and Function of the Vascular Smooth Muscle Cell
por: Li, Jing, et al.
Publicado: (2021)

AMPA-Type Glutamate Receptors Associated With Vascular Smooth Muscle Cell Subpopulations in Atherosclerosis and Vascular Injury
por: Gallina, Alessandro L., et al.
Publicado: (2021)

Skeletal Muscle-specific PGC-1α Overexpression Suppresses Atherosclerosis in Apolipoprotein E-Knockout Mice
por: Shimba, Yuki, et al.
Publicado: (2019)

The Influence of Trehalose on Atherosclerosis and Hepatic Steatosis in Apolipoprotein E Knockout Mice
por: Stachowicz, Aneta, et al.
Publicado: (2019)

FRI107 Ketogenic Diet Prevents Development Of Atherosclerotic Plaques In Apolipoprotein E Knockout Mice
por: Marzolla, Vincenzo, et al.
Publicado: (2023)

Principal function of mineralocorticoid signaling suggested by constitutive knockout of the mineralocorticoid receptor in medaka fish
por: Sakamoto, Tatsuya, et al.
Publicado: (2016)

Altered vascular smooth muscle function in the ApoE knockout mouse during the progression of atherosclerosis
por: Ewart, Marie-Ann, et al.
Publicado: (2014)

SAT-LB97 MiRNA-99a and mTOR2 Mediate Enhanced Endothelial Mineralocorticoid Receptor Signaling-Induced Activation of Sodium Channel and Endothelium Stiffness
por: Jia, Guanghong, et al.
Publicado: (2020)

Role of Aldosterone and Mineralocorticoid Receptor in Cardiovascular Aging
por: Gorini, Stefania, et al.
Publicado: (2019)

Metformin Suppresses the Progress of Diabetes-Accelerated Atherosclerosis by Inhibition of Vascular Smooth Muscle Cell Migration Through AMPK–Pdlim5 Pathway
por: Yan, Yi, et al.
Publicado: (2021)

Rivaroxaban Suppresses Atherosclerosis by Inhibiting FXa-Induced Macrophage M1 Polarization-Mediated Phenotypic Conversion of Vascular Smooth Muscle Cells
por: Ma, Yanpeng, et al.
Publicado: (2021)

Sex-specific differences in atherosclerosis, thrombospondin-1, and smooth muscle cell differentiation in metabolic syndrome versus non-metabolic syndrome mice
por: Gupta, Shreya, et al.
Publicado: (2022)

The Mineralocorticoid Receptor on Smooth Muscle Cells Promotes Tacrolimus-Induced Renal Injury in Mice
por: Figueroa, Stefanny M., et al.
Publicado: (2023)

The membrane attack complex of complement drives the progression of atherosclerosis in apolipoprotein E knockout mice
por: Lewis, Ruth D., et al.
Publicado: (2010)

Vascular cell-specific roles of mineralocorticoid receptors in pulmonary hypertension
por: Menon, Divya P., et al.
Publicado: (2021)

Aldosterone Increases Early Atherosclerosis and Promotes Plaque Inflammation Through a Placental Growth Factor‐Dependent Mechanism
por: McGraw, Adam P., et al.
Publicado: (2013)

Cardiac Mineralocorticoid Receptor and the Na(+)/H(+) Exchanger: Spilling the Beans
por: Ennis, Irene Lucía, et al.
Publicado: (2021)

Autoimmune Regulator (AIRE) Deficiency Does Not Affect Atherosclerosis and CD4 T Cell Immune Tolerance to Apolipoprotein B
por: Nettersheim, Felix Sebastian, et al.
Publicado: (2022)

Age decreases mitochondrial motility and increases mitochondrial size in vascular smooth muscle
por: Chalmers, Susan, et al.
Publicado: (2016)

The Long Non-coding RNA AC148477.2 Is a Novel Therapeutic Target Associated With Vascular Smooth Muscle Cells Proliferation of Femoral Atherosclerosis
por: Wang, Kangjie, et al.
Publicado: (2022)

Endothelial mineralocorticoid receptor contributes to systolic dysfunction induced by pressure overload without modulating cardiac hypertrophy or inflammation
por: Salvador, Ane M., et al.
Publicado: (2017)

Choline Supplementation Does Not Promote Atherosclerosis in CETP-Expressing Male Apolipoprotein E Knockout Mice
por: Collins, Heidi L., et al.
Publicado: (2022)

Case Report: Hypertriglyceridemia and Premature Atherosclerosis in a Patient With Apolipoprotein E Gene ε2ε1 Genotype
por: Limonova, Alena S., et al.
Publicado: (2021)

Low Molecular Weight Apolipoprotein(a) Phenotype Rather Than Lipoprotein(a) Is Associated With Coronary Atherosclerosis and Myocardial Infarction
por: Afanasieva, Olga I., et al.
Publicado: (2022)

Mineralocorticoid Receptor Antagonists Therapy in Resistant Hypertension: Time to Implement Guidelines!
por: Maiolino, Giuseppe, et al.
Publicado: (2015)

SAT-564 Effectiveness of Treatment with Mineralocorticoid Receptor Antagonistsin Primary Aldosteronism
por: Tezuka, Yuta, et al.
Publicado: (2020)

SAT-561 Effects of Mineralocorticoid Receptor Antagonists on Primary Aldosteronism Screening
por: Tezuka, Yuta, et al.
Publicado: (2020)

Peptidylarginine deiminase 4 deficiency in bone marrow cells prevents plaque progression without decreasing atherogenic inflammation in apolipoprotein E-knockout mice
por: Paunel-Görgülü, Adnana, et al.
Publicado: (2022)

Geranylgeranyl Transferase-I Knockout Inhibits Oxidative Injury of Vascular Smooth Muscle Cells and Attenuates Diabetes-Accelerated Atherosclerosis
por: Chen, Guo-Ping, et al.
Publicado: (2020)

The mineralocorticoid receptor knockout in medaka is further validated by glucocorticoid receptor compensation
por: Sakamoto, Tatsuya, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_tnjv1p2ladldjs4cbevdjkiarb