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The Initiation, but Not the Persistence, of Experimental Spondyloarthritis Is Dependent on Interleukin-23 Signaling

IL-17A is a central driver of spondyloarthritis (SpA), its production was originally proposed to be IL-23 dependent. Emerging preclinical and clinical evidence suggests, however, that IL-17A and IL-23 have a partially overlapping but distinct biology. We aimed to assess the extent to which IL-17A-dr...

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Detalles Bibliográficos
Autores principales: van Tok, Melissa N., Na, Songqing, Lao, Christopher R., Alvi, Marina, Pots, Desirée, van de Sande, Marleen G. H., Taurog, Joel D., Sedgwick, Jonathon D., Baeten, Dominique L., van Duivenvoorde, Leonie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046377/
https://www.ncbi.nlm.nih.gov/pubmed/30038617
http://dx.doi.org/10.3389/fimmu.2018.01550