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Mast Cell Activation and Microtubule Organization Are Modulated by Miltefosine Through Protein Kinase C Inhibition
Mast cells play an effector role in innate immunity, allergy, and inflammation. Antigen-mediated activation of mast cells initiates signaling events leading to Ca(2+) response and the release of inflammatory and allergic mediators from granules. Diseases associated with deregulated mast cell functio...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046399/ https://www.ncbi.nlm.nih.gov/pubmed/30038620 http://dx.doi.org/10.3389/fimmu.2018.01563 |