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TREM2-Dependent Effects on Microglia in Alzheimer’s Disease

Alzheimer’s disease (AD) is a late-onset dementia characterized by the deposition of amyloid plaques and formation of neurofibrillary tangles (NFTs) which lead to neuronal loss and cognitive deficits. Abnormal protein aggregates in the AD brain are also associated with reactive microglia and astrocy...

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Detalles Bibliográficos
Autores principales: Zhou, Yingyue, Ulland, Tyler K., Colonna, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046445/
https://www.ncbi.nlm.nih.gov/pubmed/30038567
http://dx.doi.org/10.3389/fnagi.2018.00202