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Nerve Growth Factor Stimulates Glioblastoma Proliferation through Notch1 Receptor Signaling

OBJECTIVE: Notch receptors are heterodimeric transmembrane proteins that regulate cell fate, such as differentiation, proliferation, and apoptosis. Dysregulated Notch pathway signaling has been observed in glioblastomas, as well as in other human malignancies. Nerve growth factor (NGF) is essential...

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Detalles Bibliográficos
Autores principales: Park, Jun Chul, Chang, In Bok, Ahn, Jun Hyong, Kim, Ji Hee, Song, Joon Ho, Moon, Seung Myung, Park, Young-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neurosurgical Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046576/
https://www.ncbi.nlm.nih.gov/pubmed/29991107
http://dx.doi.org/10.3340/jkns.2017.0219