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Phase 3, single‐arm, multicenter study of dabigatran etexilate for secondary prevention of venous thromboembolism in children: Rationale and design

BACKGROUND: Anticoagulant therapy for venous thromboembolism (VTE) in children is largely based on treatment recommendations for adults. However, differences in both physiology (ie, renal maturation and drug excretion) and developmental hemostasis must be considered when treating children, as such d...

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Detalles Bibliográficos
Autores principales: Luciani, Matteo, Albisetti, Manuela, Biss, Branislav, Bomgaars, Lisa, Brueckmann, Martina, Chalmers, Elizabeth, Gropper, Savion, Halton, Jacqueline M. L., Harper, Ruth, Huang, Fenglei, Manastirski, Ivan, Mitchell, Lesley G., Tartakovsky, Igor, Wang, Bushi, Brandão, Leonardo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046601/
https://www.ncbi.nlm.nih.gov/pubmed/30046763
http://dx.doi.org/10.1002/rth2.12093