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Identification of a Novel BRAF Thr599dup Mutation in Lung Adenocarcinoma

BRAF mutations are known as oncogenic drivers of non-small cell lung cancer (NSCLC). BRAF inhibition has demonstrated anti-tumor activity in patients with BRAF V600E mutant NSCLC. Further molecular screening for novel BRAF thr599dup mutation is warranted. The novel BRAF Thr599dup gene mutation, for...

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Detalles Bibliográficos
Autores principales: Zhang, Xuefei, Li, Mo, Lv, Desheng, Sun, Ge, Bai, Yu, Tian, Hui, Liu, Changhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter Open 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046617/
https://www.ncbi.nlm.nih.gov/pubmed/30019008
http://dx.doi.org/10.1515/med-2018-0042