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Participation of pro-inflammatory cytokines in neuropathic pain evoked by chemotherapeutic oxaliplatin via central GABAergic pathway

BACKGROUND: Neuropathic pain is observed in patients as chemotherapeutic oxaliplatin is used to treat metastatic digestive tumors; however, the mechanisms responsible for hyperalgesia are not well understood. Chronic neuroinflammation is one of the hallmarks of pathophysiology of neuropathic pain. S...

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Detalles Bibliográficos
Autores principales: Xu, Dongsheng, Zhao, Hui, Gao, Han, Zhao, Huiling, Liu, Dandan, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047101/
https://www.ncbi.nlm.nih.gov/pubmed/29900804
http://dx.doi.org/10.1177/1744806918783535