PCC0208009 enhances the anti-tumor effects of temozolomide through direct inhibition and transcriptional regulation of indoleamine 2,3-dioxygenase in glioma models

Indoleamine 2,3-dioxygenase (IDO), which is highly expressed in human glioblastoma and involved in tumor immune escape and resistance to chemotherapy, is clinically correlated with tumor progression and poor clinical outcomes, and is a promising therapeutic target for glioblastoma. IDO inhibitors ar...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Shanyue, Du, Guangying, Xue, Jiang, Ma, Jinbo, Ge, Minmin, Wang, Hongbo, Tian, Jingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047256/
https://www.ncbi.nlm.nih.gov/pubmed/29993291
http://dx.doi.org/10.1177/2058738418787991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047256/
https://www.ncbi.nlm.nih.gov/pubmed/29993291
http://dx.doi.org/10.1177/2058738418787991

Ejemplares similares