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Estimation after blinded sample size reassessment

Blinded sample size reassessment is a popular means to control the power in clinical trials if no reliable information on nuisance parameters is available in the planning phase. We investigate how sample size reassessment based on blinded interim data affects the properties of point estimates and co...

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Detalles Bibliográficos
Autores principales: Posch, Martin, Klinglmueller, Florian, König, Franz, Miller, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047306/
https://www.ncbi.nlm.nih.gov/pubmed/27697838
http://dx.doi.org/10.1177/0962280216670424