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Dynamic Variation and Reversion in the Signature Amino Acids of H7N9 Virus During Human Infection

BACKGROUND: Signature amino acids of H7N9 influenza A virus play critical roles in human adaption and pathogenesis, but their dynamic variation is unknown during disease development. METHODS: We sequentially collected respiratory samples from H7N9 patients at different timepoints and applied next-ge...

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Detalles Bibliográficos
Autores principales: Zou, Xiaohui, Guo, Qiang, Zhang, Wei, Chen, Hui, Bai, Wei, Lu, Binghuai, Zhang, Wang, Fan, Yanyan, Liu, Chao, Wang, Yeming, Zhou, Fei, Cao, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047446/
https://www.ncbi.nlm.nih.gov/pubmed/29688498
http://dx.doi.org/10.1093/infdis/jiy217