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Use of a novel camelid-inspired human antibody demonstrates the importance of MMP-14 to cancer stem cell function in the metastatic process

Matrix metalloproteinases (MMPs) are considered excellent targets for cancer therapy because of their important roles in multiple aspects of tumor growth and metastatic spread. However, not all MMPs, or even all activities of specific MMPs, promote cancer. Therefore, there is a need for highly speci...

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Detalles Bibliográficos
Autores principales: Chen, Kuan-Hui E., Chen, Chuan, Lopez, Tyler, Radecki, Kelly C., Bustamante, Karissa, Lorenson, Mary Y., Ge, Xin, Walker, Ameae M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047671/
https://www.ncbi.nlm.nih.gov/pubmed/30034628
http://dx.doi.org/10.18632/oncotarget.25654