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The relationship of CDK18 expression in breast cancer to clinicopathological parameters and therapeutic response

BACKGROUND: Cyclin-Dependent Kinases (CDKs) are established anti-cancer drug targets and a new generation of CDK inhibitors are providing clinical benefits to a sub-set of breast cancer patients. We have recently shown that human CDK18 promotes efficient cellular responses to replication stress. In...

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Detalles Bibliográficos
Autores principales: Barone, Giancarlo, Arora, Arvind, Ganesh, Anil, Abdel-Fatah, Tarek, Moseley, Paul, Ali, Reem, Chan, Stephen YT, Savva, Constantinos, Schiavone, Kristina, Carmell, Natasha, Myers, Katie N., Rakha, Emad A., Madhusudan, Srinivasan, Collis, Spencer J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047673/
https://www.ncbi.nlm.nih.gov/pubmed/30034634
http://dx.doi.org/10.18632/oncotarget.25686