Cargando…
The relationship of CDK18 expression in breast cancer to clinicopathological parameters and therapeutic response
BACKGROUND: Cyclin-Dependent Kinases (CDKs) are established anti-cancer drug targets and a new generation of CDK inhibitors are providing clinical benefits to a sub-set of breast cancer patients. We have recently shown that human CDK18 promotes efficient cellular responses to replication stress. In...
Autores principales: | Barone, Giancarlo, Arora, Arvind, Ganesh, Anil, Abdel-Fatah, Tarek, Moseley, Paul, Ali, Reem, Chan, Stephen YT, Savva, Constantinos, Schiavone, Kristina, Carmell, Natasha, Myers, Katie N., Rakha, Emad A., Madhusudan, Srinivasan, Collis, Spencer J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047673/ https://www.ncbi.nlm.nih.gov/pubmed/30034634 http://dx.doi.org/10.18632/oncotarget.25686 |
Ejemplares similares
-
Clinicopathological Significance of ATM-Chk2 Expression in Sporadic Breast Cancers: a Comprehensive Analysis in Large Cohorts()
por: Abdel-Fatah, Tarek M.A., et al.
Publicado: (2014) -
Clinicopathological significance of ataxia telangiectasia-mutated (ATM) kinase and ataxia telangiectasia-mutated and Rad3-related (ATR) kinase in MYC overexpressed breast cancers
por: Savva, Constantinos, et al.
Publicado: (2019) -
DNA repair prognostic index modelling reveals an essential role for base excision repair in influencing clinical outcomes in ER negative and triple negative breast cancers
por: Abdel-Fatah, Tarek M.A., et al.
Publicado: (2015) -
Targeting ataxia telangiectasia-mutated- and Rad3-related kinase (ATR) in PTEN-deficient breast cancers for personalized therapy
por: Al-Subhi, Nouf, et al.
Publicado: (2018) -
ERCC1 Is a Predictor of Anthracycline Resistance and Taxane Sensitivity in Early Stage or Locally Advanced Breast Cancers
por: Abdel-Fatah, Tarek M. A., et al.
Publicado: (2019)