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Sequences enriched in Alu repeats drive nuclear localization of long RNAs in human cells
Long noncoding RNAs (lncRNAs) are emerging as key players in multiple cellular pathways1, but their modes of action, and how those are dictated by sequence remain elusive. lncRNAs tend to be enriched in the nuclear fraction, whereas most mRNAs are overtly cytoplasmic2, although several studies have...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047738/ https://www.ncbi.nlm.nih.gov/pubmed/29466324 http://dx.doi.org/10.1038/nature25757 |