Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice

Diverse clustered protocadherins are thought to function in neurite morphogenesis and neuronal connectivity in the brain. Here, we report that the protocadherin alpha (Pcdha) gene cluster regulates neuronal migration during cortical development and cytoskeletal dynamics in primary cortical culture t...

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Detalles Bibliográficos
Autores principales: Fan, Li, Lu, Yichao, Shen, Xiulian, Shao, Hong, Suo, Lun, Wu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047886/
https://www.ncbi.nlm.nih.gov/pubmed/29911975
http://dx.doi.org/10.7554/eLife.35242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047886/
https://www.ncbi.nlm.nih.gov/pubmed/29911975
http://dx.doi.org/10.7554/eLife.35242

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