Amelioratory Effects of Testosterone Propionate on Age-related Renal Fibrosis via Suppression of TGF-β1/Smad Signaling and Activation of Nrf2-ARE Signaling

Androgen plays a pivotal role in the progression of renal fibrosis. However, whether exogenous androgen treatment to aged male rats can improve the age-related renal fibrosis was not explored. In our study, the changes of morphological structure, renal fibrosis, ultrastructure and renal function, th...

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Detalles Bibliográficos
Autores principales: Zhang, Guoliang, Kang, Yunxiao, Zhou, Chenming, Cui, Rui, Jia, Min, Hu, Shen, Ji, Xiaoming, Yuan, Jiayu, Cui, Huixian, Shi, Geming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048025/
https://www.ncbi.nlm.nih.gov/pubmed/30013094
http://dx.doi.org/10.1038/s41598-018-29023-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048025/
https://www.ncbi.nlm.nih.gov/pubmed/30013094
http://dx.doi.org/10.1038/s41598-018-29023-3

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