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A spike-modified Middle East respiratory syndrome coronavirus (MERS-CoV) infectious clone elicits mild respiratory disease in infected rhesus macaques

The recurrence of new human cases of Middle East respiratory syndrome coronavirus (MERS-CoV) underscores the need for effective therapeutic countermeasures. Nonhuman primate models are considered the gold standard for preclinical evaluation of therapeutic countermeasures. However, MERS-CoV-induced s...

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Detalles Bibliográficos
Autores principales: Cockrell, Adam S., Johnson, Joshua C., Moore, Ian N., Liu, David X., Bock, Kevin W., Douglas, Madeline G., Graham, Rachel L., Solomon, Jeffrey, Torzewski, Lisa, Bartos, Christopher, Hart, Randy, Baric, Ralph S., Johnson, Reed F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048037/
https://www.ncbi.nlm.nih.gov/pubmed/30013082
http://dx.doi.org/10.1038/s41598-018-28900-1