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A spike-modified Middle East respiratory syndrome coronavirus (MERS-CoV) infectious clone elicits mild respiratory disease in infected rhesus macaques
The recurrence of new human cases of Middle East respiratory syndrome coronavirus (MERS-CoV) underscores the need for effective therapeutic countermeasures. Nonhuman primate models are considered the gold standard for preclinical evaluation of therapeutic countermeasures. However, MERS-CoV-induced s...
Autores principales: | Cockrell, Adam S., Johnson, Joshua C., Moore, Ian N., Liu, David X., Bock, Kevin W., Douglas, Madeline G., Graham, Rachel L., Solomon, Jeffrey, Torzewski, Lisa, Bartos, Christopher, Hart, Randy, Baric, Ralph S., Johnson, Reed F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048037/ https://www.ncbi.nlm.nih.gov/pubmed/30013082 http://dx.doi.org/10.1038/s41598-018-28900-1 |
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