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Design principles of the paradoxical feedback between pancreatic alpha and beta cells
Mammalian glucose homeostasis is controlled by the antagonistic hormones insulin and glucagon, secreted by pancreatic beta and alpha cells respectively. These two cell types are adjacently located in the islets of Langerhans and affect each others’ secretions in a paradoxical manner: while insulin i...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048053/ https://www.ncbi.nlm.nih.gov/pubmed/30013127 http://dx.doi.org/10.1038/s41598-018-29084-4 |