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Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b

Reciprocal interactions between B and follicular T helper (Tfh) cells orchestrate the germinal center (GC) reaction, a hallmark of humoral immunity. Abnormal GC responses could lead to the production of pathogenic autoantibodies and the development of autoimmunity. Here we show that miR-146a control...

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Detalles Bibliográficos
Autores principales: Cho, Sunglim, Lee, Hyang-Mi, Yu, I-Shing, Choi, Youn Soo, Huang, Hsi-Yuan, Hashemifar, Somaye Sadat, Lin, Ling-Li, Chen, Mei-Chi, Afanasiev, Nikita D., Khan, Aly Azeem, Lin, Shu-Wha, Rudensky, Alexander Y., Crotty, Shane, Lu, Li-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048122/
https://www.ncbi.nlm.nih.gov/pubmed/30013024
http://dx.doi.org/10.1038/s41467-018-05196-3