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In utero gene expression in the Slc39a8(neo/neo) knockdown mouse

Slc39a8 encodes ZIP8, a divalent cation/bicarbonate symporter expressed in pluripotent mouse embryonic stem cells, and therefore ubiquitous in adult tissues; ZIP8 influxes Zn(2+), Mn(2+) and Fe(2+). Slc39a8(neo/neo) knockdown mice exhibit 10–15% of wild-type ZIP8 mRNA and protein levels, and show pl...

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Detalles Bibliográficos
Autores principales: Chen, Jing, Gálvez-Peralta, Marina, Zhang, Xiang, Deng, Jingyuan, Liu, Zijuan, Nebert, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048144/
https://www.ncbi.nlm.nih.gov/pubmed/30013175
http://dx.doi.org/10.1038/s41598-018-29109-y