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Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo

Photoacoustic (PA) computed tomography (PACT) benefits from genetically encoded probes with photochromic behavior, which dramatically increase detection sensitivity and specificity through photoswitching and differential imaging. Starting with a DrBphP bacterial phytochrome, we have engineered a nea...

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Detalles Bibliográficos
Autores principales: Li, Lei, Shemetov, Anton A., Baloban, Mikhail, Hu, Peng, Zhu, Liren, Shcherbakova, Daria M., Zhang, Ruiying, Shi, Junhui, Yao, Junjie, Wang, Lihong V., Verkhusha, Vladislav V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048155/
https://www.ncbi.nlm.nih.gov/pubmed/30013153
http://dx.doi.org/10.1038/s41467-018-05231-3