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Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo
Photoacoustic (PA) computed tomography (PACT) benefits from genetically encoded probes with photochromic behavior, which dramatically increase detection sensitivity and specificity through photoswitching and differential imaging. Starting with a DrBphP bacterial phytochrome, we have engineered a nea...
Autores principales: | Li, Lei, Shemetov, Anton A., Baloban, Mikhail, Hu, Peng, Zhu, Liren, Shcherbakova, Daria M., Zhang, Ruiying, Shi, Junhui, Yao, Junjie, Wang, Lihong V., Verkhusha, Vladislav V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048155/ https://www.ncbi.nlm.nih.gov/pubmed/30013153 http://dx.doi.org/10.1038/s41467-018-05231-3 |
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