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Gabrb2-knockout mice displayed schizophrenia-like and comorbid phenotypes with interneuron–astrocyte–microglia dysregulation

Intronic polymorphisms of the GABA(A) receptor β(2) subunit gene (GABRB2) under adaptive evolution were associated with schizophrenia and reduced expression, especially of the long isoform which differs in electrophysiological properties from the short isoform. The present study was directed to exam...

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Detalles Bibliográficos
Autores principales: Yeung, Rigil K., Xiang, Zheng-Hua, Tsang, Shui-Ying, Li, Rui, Ho, Timothy Y. C., Li, Qi, Hui, Chok-King, Sham, Pak-Chung, Qiao, Ming-Qi, Xue, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048160/
https://www.ncbi.nlm.nih.gov/pubmed/30013074
http://dx.doi.org/10.1038/s41398-018-0176-9