In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer

Genetic aberrations driving pro-oncogenic and pro-metastatic activity remain an elusive target in the quest of precision oncology. To identify such drivers, we use an animal model of KRAS-mutant lung adenocarcinoma to perform an in vivo functional screen of 217 genetic aberrations selected from lung...

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Detalles Bibliográficos
Autores principales: Grzeskowiak, Caitlin L., Kundu, Samrat T., Mo, Xiulei, Ivanov, Andrei A., Zagorodna, Oksana, Lu, Hengyu, Chapple, Richard H., Tsang, Yiu Huen, Moreno, Daniela, Mosqueda, Maribel, Eterovic, Karina, Fradette, Jared J., Ahmad, Sumreen, Chen, Fengju, Chong, Zechen, Chen, Ken, Creighton, Chad J., Fu, Haian, Mills, Gordon B., Gibbons, Don L., Scott, Kenneth L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048166/
https://www.ncbi.nlm.nih.gov/pubmed/30013058
http://dx.doi.org/10.1038/s41467-018-04572-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048166/
https://www.ncbi.nlm.nih.gov/pubmed/30013058
http://dx.doi.org/10.1038/s41467-018-04572-3

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