Cargando…

Water structure changes in oxime-mediated reactivation process of phosphorylated human acetylcholinesterase

The role of water in oxime-mediated reactivation of phosphylated cholinesterases (ChEs) has been asked with recurrence. To investigate oximate water structure changes in this reaction, reactivation of paraoxon-inhibited human acetylcholinesterase (AChE) was performed by the oxime asoxime (HI-6) at d...

Descripción completa

Detalles Bibliográficos
Autores principales: Zueva, Irina V., Lushchekina, Sofya V., Masson, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048214/
https://www.ncbi.nlm.nih.gov/pubmed/29773682
http://dx.doi.org/10.1042/BSR20180609