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Water structure changes in oxime-mediated reactivation process of phosphorylated human acetylcholinesterase
The role of water in oxime-mediated reactivation of phosphylated cholinesterases (ChEs) has been asked with recurrence. To investigate oximate water structure changes in this reaction, reactivation of paraoxon-inhibited human acetylcholinesterase (AChE) was performed by the oxime asoxime (HI-6) at d...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048214/ https://www.ncbi.nlm.nih.gov/pubmed/29773682 http://dx.doi.org/10.1042/BSR20180609 |