MicroRNA-199a Inhibits Cellular Autophagy and Downregulates IFN-β Expression by Targeting TBK1 in Mycobacterium bovis Infected Cells

The mechanism by which microRNAs (miRNAs) modulate innate immunity and autophagy has not been fully elucidated in Mycobacterium bovis (M. bovis) infections. In this study, we identified that miR-199a inhibited key innate immune responses and autophagy in murine macrophages infected with M. bovis. Us...

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Detalles Bibliográficos
Autores principales: Wang, Jie, Hussain, Tariq, Yue, Ruichao, Liao, Yi, Li, Qiang, Yao, Jiao, Song, Yinjuan, Sun, Xin, Wang, Nan, Xu, Lei, Sreevatsan, Srinand, Zhao, Deming, Zhou, Xiangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048223/
https://www.ncbi.nlm.nih.gov/pubmed/30042930
http://dx.doi.org/10.3389/fcimb.2018.00238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048223/
https://www.ncbi.nlm.nih.gov/pubmed/30042930
http://dx.doi.org/10.3389/fcimb.2018.00238

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