Cargando…
MicroRNA-199a Inhibits Cellular Autophagy and Downregulates IFN-β Expression by Targeting TBK1 in Mycobacterium bovis Infected Cells
The mechanism by which microRNAs (miRNAs) modulate innate immunity and autophagy has not been fully elucidated in Mycobacterium bovis (M. bovis) infections. In this study, we identified that miR-199a inhibited key innate immune responses and autophagy in murine macrophages infected with M. bovis. Us...
Autores principales: | Wang, Jie, Hussain, Tariq, Yue, Ruichao, Liao, Yi, Li, Qiang, Yao, Jiao, Song, Yinjuan, Sun, Xin, Wang, Nan, Xu, Lei, Sreevatsan, Srinand, Zhao, Deming, Zhou, Xiangmei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048223/ https://www.ncbi.nlm.nih.gov/pubmed/30042930 http://dx.doi.org/10.3389/fcimb.2018.00238 |
Ejemplares similares
-
The Central Role of IFI204 in IFN-β Release and Autophagy Activation during Mycobacterium bovis Infection
por: Chunfa, Liu, et al.
Publicado: (2017) -
cGAS/STING/TBK1/IRF3 Signaling Pathway Activates BMDCs Maturation Following Mycobacterium bovis Infection
por: Li, Qiang, et al.
Publicado: (2019) -
AIM2 inhibits autophagy and IFN-β production during M. bovis infection
por: Liu, Chunfa, et al.
Publicado: (2016) -
The role of IL-10 in Mycobacterium avium subsp. paratuberculosis infection
por: Hussain, Tariq, et al.
Publicado: (2016) -
PP2Ac Modulates AMPK-Mediated Induction of Autophagy in Mycobacterium bovis-Infected Macrophages
por: Hussain, Tariq, et al.
Publicado: (2019)