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The Putative De-N-acetylase DnpA Contributes to Intracellular and Biofilm-Associated Persistence of Pseudomonas aeruginosa Exposed to Fluoroquinolones

Persisters are the fraction of antibiotic-exposed bacteria transiently refractory to killing and are recognized as a cause of antibiotic treatment failure. The putative de-N-acetylase DnpA increases persister levels in Pseudomonas aeruginosa upon exposure to fluoroquinolones in broth. In this study...

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Detalles Bibliográficos
Autores principales: Khandekar, Shaunak, Liebens, Veerle, Fauvart, Maarten, Tulkens, Paul M., Michiels, Jan, Van Bambeke, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048251/
https://www.ncbi.nlm.nih.gov/pubmed/30042739
http://dx.doi.org/10.3389/fmicb.2018.01455