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Acidosis and Phosphate Directly Reduce Myosin’s Force-Generating Capacity Through Distinct Molecular Mechanisms
Elevated levels of the metabolic by-products, including acidosis (i.e., high [H(+)]) and phosphate (P(i)) are putative agents of muscle fatigue; however, the mechanism through which they affect myosin’s function remain unclear. To elucidate these mechanisms, we directly examined the effect of acidos...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048269/ https://www.ncbi.nlm.nih.gov/pubmed/30042692 http://dx.doi.org/10.3389/fphys.2018.00862 |