Cardioprotective Properties of Human Platelets Are Lost in Uncontrolled Diabetes Mellitus: A Study in Isolated Rat Hearts

Platelets affect myocardial damage from ischemia/reperfusion. Redox-dependent sphingosine-1-phosphate production and release are altered in diabetic platelets. Sphingosine-1-phosphate is a double-edged sword for ischemia/reperfusion injury. Therefore, we aimed to verify whether: (1) human healthy- o...

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Detalles Bibliográficos
Autores principales: Russo, Isabella, Femminò, Saveria, Barale, Cristina, Tullio, Francesca, Geuna, Stefano, Cavalot, Franco, Pagliaro, Pasquale, Penna, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048273/
https://www.ncbi.nlm.nih.gov/pubmed/30042694
http://dx.doi.org/10.3389/fphys.2018.00875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048273/
https://www.ncbi.nlm.nih.gov/pubmed/30042694
http://dx.doi.org/10.3389/fphys.2018.00875

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