Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration

Ferroptosis is a newly described form of regulated cell death, distinct from apoptosis, necroptosis and other forms of cell death. Ferroptosis is induced by disruption of glutathione synthesis or inhibition of glutathione peroxidase 4, exacerbated by iron, and prevented by radical scavengers such as...

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Detalles Bibliográficos
Autores principales: Abdalkader, Moataz, Lampinen, Riikka, Kanninen, Katja M., Malm, Tarja M., Liddell, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048292/
https://www.ncbi.nlm.nih.gov/pubmed/30042655
http://dx.doi.org/10.3389/fnins.2018.00466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048292/
https://www.ncbi.nlm.nih.gov/pubmed/30042655
http://dx.doi.org/10.3389/fnins.2018.00466

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