Elucidating T Cell Activation-Dependent Mechanisms for Bifurcation of Regulatory and Effector T Cell Differentiation by Multidimensional and Single-Cell Analysis

In T cells, T cell receptor (TCR) signaling initiates downstream transcriptional mechanisms for T cell activation and differentiation. Foxp3-expressing regulatory T cells (Treg) require TCR signals for their suppressive function and maintenance in the periphery. It is, however, unclear how TCR signa...

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Detalles Bibliográficos
Autores principales: Bradley, Alla, Hashimoto, Tetsuo, Ono, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048294/
https://www.ncbi.nlm.nih.gov/pubmed/30061879
http://dx.doi.org/10.3389/fimmu.2018.01444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048294/
https://www.ncbi.nlm.nih.gov/pubmed/30061879
http://dx.doi.org/10.3389/fimmu.2018.01444

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