Casein Kinase 1δ/ε Inhibitor, PF670462 Attenuates the Fibrogenic Effects of Transforming Growth Factor-β in Pulmonary Fibrosis

Transforming growth factor-beta (TGF-β) is a major mediator of fibrotic diseases, including idiopathic pulmonary fibrosis (IPF). However, therapeutic global inhibition of TGF-β is limited by unwanted immunosuppression and mitral valve defects. We performed an extensive literature search to uncover a...

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Detalles Bibliográficos
Autores principales: Keenan, Christine R., Langenbach, Shenna Y., Jativa, Fernando, Harris, Trudi, Li, Meina, Chen, Qianyu, Xia, Yuxiu, Gao, Bryan, Schuliga, Michael J., Jaffar, Jade, Prodanovic, Danica, Tu, Yan, Berhan, Asres, Lee, Peter V. S., Westall, Glen P., Stewart, Alastair G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048361/
https://www.ncbi.nlm.nih.gov/pubmed/30042678
http://dx.doi.org/10.3389/fphar.2018.00738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048361/
https://www.ncbi.nlm.nih.gov/pubmed/30042678
http://dx.doi.org/10.3389/fphar.2018.00738

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