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Total polysaccharides of the Sijunzi decoction attenuate tumor necrosis factor-α-induced damage to the barrier function of a Caco-2 cell monolayer via the nuclear factor-κB-myosin light chain kinase-myosin light chain pathway

AIM: To explore the protective effects and underlying mechanisms of total polysaccharides of the Sijunzi decoction (TPSJ) on the epithelial barriers in vitro. METHODS: Caco-2 cell monolayers were treated with or without TPSJ in the presence or absence of TNF-α, and paracellular permeability and tran...

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Detalles Bibliográficos
Autores principales: Lu, Yue, Li, Leng, Zhang, Jin-Wei, Zhong, Xiao-Qin, Wei, Jian-An, Han, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048434/
https://www.ncbi.nlm.nih.gov/pubmed/30018481
http://dx.doi.org/10.3748/wjg.v24.i26.2867