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Structure of the Lassa virus glycan shield provides a model for immunological resistance

Lassa virus is an Old World arenavirus endemic to West Africa that causes severe hemorrhagic fever. Vaccine development has focused on the envelope glycoprotein complex (GPC) that extends from the virion envelope. The often inadequate antibody immune response elicited by both vaccine and natural inf...

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Detalles Bibliográficos
Autores principales: Watanabe, Yasunori, Raghwani, Jayna, Allen, Joel D., Seabright, Gemma E., Li, Sai, Moser, Felipe, Huiskonen, Juha T., Strecker, Thomas, Bowden, Thomas A., Crispin, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048489/
https://www.ncbi.nlm.nih.gov/pubmed/29941589
http://dx.doi.org/10.1073/pnas.1803990115