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Gene expression distribution deconvolution in single-cell RNA sequencing

Single-cell RNA sequencing (scRNA-seq) enables the quantification of each gene’s expression distribution across cells, thus allowing the assessment of the dispersion, nonzero fraction, and other aspects of its distribution beyond the mean. These statistical characterizations of the gene expression d...

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Detalles Bibliográficos
Autores principales: Wang, Jingshu, Huang, Mo, Torre, Eduardo, Dueck, Hannah, Shaffer, Sydney, Murray, John, Raj, Arjun, Li, Mingyao, Zhang, Nancy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048536/
https://www.ncbi.nlm.nih.gov/pubmed/29946020
http://dx.doi.org/10.1073/pnas.1721085115