Curcumin exerts anti-inflammatory and vasoprotective effects through amelioration of NFAT-dependent endothelin-1 production in mice with acute Chagas cardiomyopathy

OBJECTIVE: To evaluate the effects of oral therapy with Cur on T. cruzi-mediated cardiovasculopathy in acutely infected mice and analyse the in vitro response of parasite-infected human microvascular endothelial cells treated with this phytochemical. METHODS: Inflammation of heart vessels from Cur-t...

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Detalles Bibliográficos
Autores principales: Hernández, Matías, Wicz, Susana, Santamaría, Miguel H, Corral, Ricardo S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048587/
https://www.ncbi.nlm.nih.gov/pubmed/30020318
http://dx.doi.org/10.1590/0074-02760180171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048587/
https://www.ncbi.nlm.nih.gov/pubmed/30020318
http://dx.doi.org/10.1590/0074-02760180171

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