HDAC3-mediated silencing of miR-451 decreases chemosensitivity of patients with metastatic castration-resistant prostate cancer by targeting NEDD9

BACKGROUND: Treatment of metastatic castration-resistant prostate cancer (mCRPC) with docetaxel often fails due to the emergence of chemoresistance. Thus, restoring chemosensitivity to docetaxel-based therapies remains a challenge in mCRPC treatment. METHODS: microRNA (miR)-451 expression was measur...

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Detalles Bibliográficos
Autores principales: Chen, Dong-qin, Yu, Chen, Zhang, Xue-feng, Liu, Zhong-fang, Wang, Rui, Jiang, Min, Chen, Hao, Yan, Feng, Tao, Min, Chen, Long-bang, Zhu, Hong, Feng, Ji-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048672/
https://www.ncbi.nlm.nih.gov/pubmed/30034549
http://dx.doi.org/10.1177/1758835918783132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048672/
https://www.ncbi.nlm.nih.gov/pubmed/30034549
http://dx.doi.org/10.1177/1758835918783132

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