Cargando…
Rapid Cue-Specific Remodeling of the Nascent Axonal Proteome
Axonal protein synthesis and degradation are rapidly regulated by extrinsic signals during neural wiring, but the full landscape of proteomic changes remains unknown due to limitations in axon sampling and sensitivity. By combining pulsed stable isotope labeling of amino acids in cell culture with s...
Autores principales: | Cagnetta, Roberta, Frese, Christian K., Shigeoka, Toshiaki, Krijgsveld, Jeroen, Holt, Christine E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048689/ https://www.ncbi.nlm.nih.gov/pubmed/30008298 http://dx.doi.org/10.1016/j.neuron.2018.06.004 |
Ejemplares similares
-
Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons
por: Koppers, Max, et al.
Publicado: (2019) -
Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring
por: Cagnetta, Roberta, et al.
Publicado: (2019) -
On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in Axons
por: Shigeoka, Toshiaki, et al.
Publicado: (2019) -
RNA-based mechanisms underlying axon guidance
por: Shigeoka, Toshiaki, et al.
Publicado: (2013) -
RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo
por: Wong, Hovy Ho-Wai, et al.
Publicado: (2017)