Suppression of PDHX by microRNA-27b deregulates cell metabolism and promotes growth in breast cancer

BACKGROUND: The disruption of normal gene regulation due to microRNA dysfunction is a common event in cancer pathogenesis. MicroRNA-27b is an example of an oncogenic miRNA, and it is frequently upregulated in breast cancer. MicroRNAs have been found to deregulate tumor metabolism, which typically ma...

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Detalles Bibliográficos
Autores principales: Eastlack, Steven C., Dong, Shengli, Ivan, Cristina, Alahari, Suresh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048708/
https://www.ncbi.nlm.nih.gov/pubmed/30012170
http://dx.doi.org/10.1186/s12943-018-0851-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048708/
https://www.ncbi.nlm.nih.gov/pubmed/30012170
http://dx.doi.org/10.1186/s12943-018-0851-8

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