Cargando…
Suppression of PDHX by microRNA-27b deregulates cell metabolism and promotes growth in breast cancer
BACKGROUND: The disruption of normal gene regulation due to microRNA dysfunction is a common event in cancer pathogenesis. MicroRNA-27b is an example of an oncogenic miRNA, and it is frequently upregulated in breast cancer. MicroRNAs have been found to deregulate tumor metabolism, which typically ma...
Autores principales: | Eastlack, Steven C., Dong, Shengli, Ivan, Cristina, Alahari, Suresh K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048708/ https://www.ncbi.nlm.nih.gov/pubmed/30012170 http://dx.doi.org/10.1186/s12943-018-0851-8 |
Ejemplares similares
-
MicroRNA and Breast Cancer: Understanding Pathogenesis, Improving Management
por: Eastlack, Steven C., et al.
Publicado: (2015) -
MicroRNA-26a regulates glucose metabolism by direct targeting PDHX in colorectal cancer cells
por: Chen, Bing, et al.
Publicado: (2014) -
Identification of PDHX as a metabolic target for esophageal squamous cell carcinoma
por: Inoue, Jun, et al.
Publicado: (2021) -
Expression of long noncoding RNA MALAT1 correlates with increased levels of Nischarin and inhibits oncogenic cell functions in breast cancer
por: Eastlack, Steven C., et al.
Publicado: (2018) -
Deregulated Cardiac Specific MicroRNAs in Postnatal Heart Growth
por: Yu, Pujiao, et al.
Publicado: (2016)