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C-terminal truncation of α-synuclein promotes amyloid fibril amplification at physiological pH
Parkinson's disease is one of the major neurodegenerative disorders affecting the ageing populations of the modern world. One of the hallmarks of this disease is the deposition of aggregates, mainly of the small pre-synaptic protein α-synuclein (AS), in the brains of patients. Several very sign...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048717/ https://www.ncbi.nlm.nih.gov/pubmed/30061982 http://dx.doi.org/10.1039/c8sc01109e |