BMP4 promotes hepatocellular carcinoma proliferation by autophagy activation through JNK1-mediated Bcl-2 phosphorylation

BACKGROUND: Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP4), a member of the transforming growth factor (TGF-β) family of regulatory proteins, plays a crucial role in human malignancies. However, whether BMP4 contributes to...

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Detalles Bibliográficos
Autores principales: Deng, Ganlu, Zeng, Shan, Qu, Yanling, Luo, Qingqing, Guo, Cao, Yin, Ling, Han, Ying, Li, Yiyi, Cai, Changjing, Fu, Yaojie, Shen, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048721/
https://www.ncbi.nlm.nih.gov/pubmed/30012194
http://dx.doi.org/10.1186/s13046-018-0828-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048721/
https://www.ncbi.nlm.nih.gov/pubmed/30012194
http://dx.doi.org/10.1186/s13046-018-0828-x

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